{"created":"2023-06-20T13:45:26.203698+00:00","id":195,"links":{},"metadata":{"_buckets":{"deposit":"03d9972a-4d3b-45d2-a2ea-6c1cf47419c2"},"_deposit":{"created_by":12,"id":"195","owners":[12],"pid":{"revision_id":0,"type":"depid","value":"195"},"status":"published"},"_oai":{"id":"oai:khsu.repo.nii.ac.jp:00000195","sets":["22:81:84"]},"author_link":["23","300","299","297","326"],"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"15","bibliographicPageEnd":"82","bibliographicPageStart":"73","bibliographic_titles":[{"bibliographic_title":"熊本保健科学大学研究誌"},{"bibliographic_title":"Journal of Kumamoto Health Science University","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"舌には味覚だけではなく体性感覚を伝える感覚神経が，密に分布している。これまでの先行\n研究において，舌の味覚受容については多くの研究がなされているが，舌のもう一つの重要な\n役割である体性感覚についての研究は少ない。特に舌への触・圧覚刺激のみの刺激と脳の記憶\n力に関する詳細な報告は少なく，今日に至っても明らかではない。そこで，本研究では舌への\n触・圧覚刺激が, 脳の発達と記憶力・学習能力に及ぼす影響を行動学的手法，免疫学的手法を用\nいて検討をした。その結果，学習・記憶機能評価である8方向放射状迷路試験とStep-down 試験\nでは，刺激強度0.73 newton（N）群では，コントロール群に対し記憶力の増強が認められた。\nさらに，舌への触・圧覚刺激は，ラット海馬におけるc-Fos 陽性細胞増加させた。しかし，\nBrdU 陽性細胞やBDNF mRNA の若干の増加は認めたが，有意差を認めるには至らなかった。\nBrdU 陽性細胞やBDNF mRNA のを増加させた。これらの結果から，舌への触・圧覚刺激は，\nラットの海馬を活性化させ，成長因子の増加や細胞新生を促進させることで，記憶力の増強に\n影響した可能性が示唆された。","subitem_description_type":"Abstract"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"熊本保健科学大学"}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"24335002","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"田中, 哲子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"行平, 崇"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"西, 健太朗"}],"nameIdentifiers":[{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":""}],"affiliationNames":[{"affiliationName":""}]}],"creatorNames":[{"creatorName":"久保, 高明","creatorNameLang":"ja"}],"familyNames":[{}],"givenNames":[{}],"nameIdentifiers":[{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":""}],"affiliationNames":[{"affiliationName":""}]}],"creatorNames":[{"creatorName":"申, 敏哲","creatorNameLang":"ja"},{"creatorName":"Shin , MinChul","creatorNameLang":"en"}],"familyNames":[{},{}],"givenNames":[{},{}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-06-06"}],"displaytype":"detail","filename":"08-tanaka-p073-082.pdf","filesize":[{"value":"5.1 MB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"08-tanaka-p073-082","url":"https://khsu.repo.nii.ac.jp/record/195/files/08-tanaka-p073-082.pdf"},"version_id":"9e023d56-4e4f-4679-8fff-c0828aa17bf1"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"舌刺激","subitem_subject_scheme":"Other"},{"subitem_subject":"記憶力","subitem_subject_scheme":"Other"},{"subitem_subject":"ラット","subitem_subject_scheme":"Other"},{"subitem_subject":"tongue stimulation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"memory/learning ability","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"rat","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"舌への刺激がラットの記憶力に及ぼす影響","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"舌への刺激がラットの記憶力に及ぼす影響"},{"subitem_title":"Influences of tongue stimulation upon spatial memory/learning ability in rat","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"12","path":["84"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-06-07"},"publish_date":"2018-06-07","publish_status":"0","recid":"195","relation_version_is_last":true,"title":["舌への刺激がラットの記憶力に及ぼす影響"],"weko_creator_id":"12","weko_shared_id":-1},"updated":"2024-04-11T08:34:08.752966+00:00"}