{"created":"2023-06-20T13:45:27.391909+00:00","id":221,"links":{},"metadata":{"_buckets":{"deposit":"6a12345f-6204-4ceb-9da6-b65d01b9e66e"},"_deposit":{"created_by":12,"id":"221","owners":[12],"pid":{"revision_id":0,"type":"depid","value":"221"},"status":"published"},"_oai":{"id":"oai:khsu.repo.nii.ac.jp:00000221","sets":["22:81:88"]},"author_link":["347","348"],"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"17","bibliographicPageEnd":"9","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"熊本保健科学大学研究誌"},{"bibliographic_title":"Journal of Kumamoto Health Science University","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"　血小板の母細胞である巨核球は,造血幹細胞から巨核球系特異的サイトカインである\nthrombopoietin(TPO)の制御を受け，分化・成熟し，分化の最終段階で胞体突起を形成する。\nこの胞体の先端が断裂することにより血小板が産生される。以前より，培養巨核球がTPO 存在\n下においてもアポトーシスに陥りやすいことから，血小板産生過程にアポトーシスが関与する\nという仮説が提唱されてきた。そこで本稿では，巨核球造血におけるアポトーシスの関与につ\nいて概説する。","subitem_description_type":"Abstract"}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2433-5002","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"上妻, 行則"}],"nameIdentifiers":[{"nameIdentifier":"347","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"登尾, 一平"}],"nameIdentifiers":[{"nameIdentifier":"348","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-05-01"}],"displaytype":"detail","filename":"p01-09-kozuma.pdf","filesize":[{"value":"1.4 MB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"p01-09-kozuma","url":"https://khsu.repo.nii.ac.jp/record/221/files/p01-09-kozuma.pdf"},"version_id":"5a96506d-b8d7-4672-975a-f85dafa67703"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"巨核球","subitem_subject_scheme":"Other"},{"subitem_subject":"アポトーシス","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"巨核球造血におけるアポトーシス関連タンパクの役割","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"巨核球造血におけるアポトーシス関連タンパクの役割"},{"subitem_title":"The role of apoptosis-related proteins during megakaryopoiesis.","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"12","path":["88"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-05-01"},"publish_date":"2020-05-01","publish_status":"0","recid":"221","relation_version_is_last":true,"title":["巨核球造血におけるアポトーシス関連タンパクの役割"],"weko_creator_id":"12","weko_shared_id":-1},"updated":"2023-06-20T13:50:13.208611+00:00"}