{"created":"2023-06-20T13:45:27.669024+00:00","id":225,"links":{},"metadata":{"_buckets":{"deposit":"df9b146b-8771-4c38-9fcc-5970de35fd2e"},"_deposit":{"created_by":12,"id":"225","owners":[12],"pid":{"revision_id":0,"type":"depid","value":"225"},"status":"published"},"_oai":{"id":"oai:khsu.repo.nii.ac.jp:00000225","sets":["22:81:88"]},"author_link":["357","359","356","355","358"],"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"17","bibliographicPageEnd":"58","bibliographicPageStart":"49","bibliographic_titles":[{"bibliographic_title":"熊本保健科学大学研究誌"},{"bibliographic_title":"Journal of Kumamoto Health Science University","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"　舌の味覚受容については多くの研究がされているが，舌のもう一つの重要な役割である体性\n感覚についての研究は少ない。 近年，我々は舌への触・圧覚刺激がラットの海馬を活性化させ，\n成長因子の増加や細胞新生を促進させることで，記憶力の増強に影響した可能性を報告した。\nしかし，舌への痛覚，温・冷覚のみの刺激と記憶力と学習能力に関する詳細な報告は少なく，\n未だ明らかではない。そこで，本研究では舌への痛覚，温・冷覚刺激がラットの記憶と学習能\n力に及ぼす影響を行動学的手法，免疫学的手法を用いて検討をした。その結果，学習・記憶機\n能評価である8方向放射状迷路試験とStep-down 試験では，痛覚刺激群でコントロール群に対\nし記憶力の増強が認められたが，温・冷覚刺激群では記憶力の若干の増減がみられたものの有\n意差は認められなかった。海馬でのc-Fos，BrdU 陽性細胞の検討でも，痛覚刺激群でコント\nロール群に対し，有意な増加が認められたが，温・冷覚刺激群では若干の増加がみられたもの\nの有意差はなかった。これらの結果から，舌への痛覚刺激は，ラットの海馬を活性化させ，成\n長因子の増加や細胞新生を促進させることで，記憶力の増強に影響した可能性が示唆された。\nしかし，温・冷覚刺激に関して，今回の研究では有意差は見られず，今後刺激の強度について\n検証していく必要があると考えられる。","subitem_description_type":"Abstract"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"熊本保健科学大学"}]},"item_10002_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA12816509","subitem_source_identifier_type":"NCID"}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2433-5002","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"行平, 崇"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"小牧, 龍二"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"福永, 貴之"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"田中, 哲子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"申, 敏哲"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-05-01"}],"displaytype":"detail","filename":"p49-58-yukihira.pdf","filesize":[{"value":"1.3 MB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"p49-58-yukihira","url":"https://khsu.repo.nii.ac.jp/record/225/files/p49-58-yukihira.pdf"},"version_id":"6c388a53-2874-49ee-9d1f-d663a8a859f7"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"舌刺激","subitem_subject_scheme":"Other"},{"subitem_subject":"痛覚","subitem_subject_scheme":"Other"},{"subitem_subject":"温・冷覚","subitem_subject_scheme":"Other"},{"subitem_subject":"記憶力","subitem_subject_scheme":"Other"},{"subitem_subject":"ラット","subitem_subject_scheme":"Other"},{"subitem_subject":"tongue stimulation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"memory and learning","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"rat","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"舌への痛覚,温・冷覚刺激がラットの記憶力と学習能力に及ぼす影響","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"舌への痛覚,温・冷覚刺激がラットの記憶力と学習能力に及ぼす影響"},{"subitem_title":"Effects of pain, warmth, and cold on rat's memory and learning ability via tongue stimulation","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"12","path":["88"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-05-01"},"publish_date":"2020-05-01","publish_status":"0","recid":"225","relation_version_is_last":true,"title":["舌への痛覚,温・冷覚刺激がラットの記憶力と学習能力に及ぼす影響"],"weko_creator_id":"12","weko_shared_id":-1},"updated":"2023-06-20T13:50:08.850323+00:00"}