{"created":"2023-06-20T13:45:29.252054+00:00","id":255,"links":{},"metadata":{"_buckets":{"deposit":"60bcabbb-9858-4290-86b6-d9bfa08d33ed"},"_deposit":{"created_by":12,"id":"255","owners":[12],"pid":{"revision_id":0,"type":"depid","value":"255"},"status":"published"},"_oai":{"id":"oai:khsu.repo.nii.ac.jp:00000255","sets":["71"]},"author_link":["426"],"item_10007_date_8":{"attribute_name":"報告年度","attribute_value_mlt":[{"subitem_date_issued_datetime":"2018","subitem_date_issued_type":"Issued"}]},"item_10007_description_10":{"attribute_name":"研究代表者番号","attribute_value_mlt":[{"subitem_description":"10321944","subitem_description_type":"Other"}]},"item_10007_description_11":{"attribute_name":"研究機関","attribute_value_mlt":[{"subitem_description":"熊本保健科学大学","subitem_description_type":"Other"}]},"item_10007_description_13":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要：申請者が現所属先へと異動となった後、熊本地震により動物管理施設が損傷を受け、遺伝子改変マウスの受け入れ等、計画した実験の遂行が困難となったため、マウスの胎仔卵巣を構成する生殖細胞と生殖腺体細胞の形成を共通で制御する分子機構の解明を目指して研究を進めた。我々は、始原生殖細胞と生殖腺体細胞の前駆細胞の両方の形成を制御する転写因子Six1とSix4を見出し、ポジティブフィードバック機構を介してそれぞれの運命決定因子の発現を制御していることを明らかにした。","subitem_description_type":"Abstract"}]},"item_10007_description_9":{"attribute_name":"研究課題番号","attribute_value_mlt":[{"subitem_description":"15K07080","subitem_description_type":"Other"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-03-08"}],"displaytype":"detail","filename":"kaken.nii.ac.jp_15K07080seika.pdf","filesize":[{"value":"109.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"kaken.nii.ac.jp_15K07080seika","url":"https://khsu.repo.nii.ac.jp/record/255/files/kaken.nii.ac.jp_15K07080seika.pdf"},"version_id":"15e97676-d62e-462b-9553-3fa4ff5fed67"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"生殖細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"マウス","subitem_subject_scheme":"Other"},{"subitem_subject":"Six1","subitem_subject_scheme":"Other"},{"subitem_subject":"Six4","subitem_subject_scheme":"Other"},{"subitem_subject":"生殖腺","subitem_subject_scheme":"Other"},{"subitem_subject":"性分化","subitem_subject_scheme":"Other"},{"subitem_subject":"卵巣","subitem_subject_scheme":"Other"},{"subitem_subject":"顆粒膜細胞","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_researcher":{"attribute_name":"研究代表者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"田中 , 聡"}],"nameIdentifiers":[{"nameIdentifier":"426","nameIdentifierScheme":"WEKO"}]}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"マウス卵巣で機能的な卵胞形成に寄与する顆粒膜細胞の形成機構の解明","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"マウス卵巣で機能的な卵胞形成に寄与する顆粒膜細胞の形成機構の解明"},{"subitem_title":"Analysis of the formation of cell lineages in a mouse embryonic ovary","subitem_title_language":"en"}]},"item_type_id":"10007","owner":"12","path":["71"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-03-08"},"publish_date":"2022-03-08","publish_status":"0","recid":"255","relation_version_is_last":true,"title":["マウス卵巣で機能的な卵胞形成に寄与する顆粒膜細胞の形成機構の解明"],"weko_creator_id":"12","weko_shared_id":-1},"updated":"2023-06-20T13:49:35.016548+00:00"}