{"created":"2023-06-20T13:45:29.719470+00:00","id":264,"links":{},"metadata":{"_buckets":{"deposit":"4ec10cef-c574-41b6-bedc-26bf7822d15b"},"_deposit":{"created_by":12,"id":"264","owners":[12],"pid":{"revision_id":0,"type":"depid","value":"264"},"status":"published"},"_oai":{"id":"oai:khsu.repo.nii.ac.jp:00000264","sets":["71"]},"author_link":["122"],"item_10007_date_8":{"attribute_name":"報告年度","attribute_value_mlt":[{"subitem_date_issued_datetime":"2017","subitem_date_issued_type":"Issued"}]},"item_10007_description_10":{"attribute_name":"研究代表者番号","attribute_value_mlt":[{"subitem_description":"70259745","subitem_description_type":"Other"}]},"item_10007_description_11":{"attribute_name":"研究機関","attribute_value_mlt":[{"subitem_description":"熊本保健科学大学","subitem_description_type":"Other"}]},"item_10007_description_13":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要：吸入麻酔に用いられるガス性麻酔薬のキセノン（Xe）が興奮性と抑制性のシナプス伝達をどのように修飾するかを、機械的に単離したラット海馬CA3ニューロンのシナプス・ブートン標本を用いて検討した。その結果、Xeは興奮性グルタミン酸伝達機構をシナプス前終末部とシナプス後膜上のシナプス外受容体の両方で抑制するが、前者により強く作用する。抑制性GABA伝達機構ではシナプス前終末部のみを抑制した。本成果はXeの作用部位は興奮・抑制系共にシナプス後膜側のみであるとの今迄の報告の全てを改める新知見である。","subitem_description_type":"Abstract"}]},"item_10007_description_9":{"attribute_name":"研究課題番号","attribute_value_mlt":[{"subitem_description":"26462349","subitem_description_type":"Other"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-03-08"}],"displaytype":"detail","filename":"kaken.nii.ac.jp_26462349seika.pdf","filesize":[{"value":"288.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"kaken.nii.ac.jp_26462349seika","url":"https://khsu.repo.nii.ac.jp/record/264/files/kaken.nii.ac.jp_26462349seika.pdf"},"version_id":"9d9f5e66-9bf3-4c37-8bdd-5cdf4e90916f"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"シナプス","subitem_subject_scheme":"Other"},{"subitem_subject":"キセノン","subitem_subject_scheme":"Other"},{"subitem_subject":"GABA","subitem_subject_scheme":"Other"},{"subitem_subject":"グルタミン酸","subitem_subject_scheme":"Other"},{"subitem_subject":"ブートン","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_researcher":{"attribute_name":"研究代表者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"野中, 喜久","creatorNameLang":"ja"}],"familyNames":[{"familyName":"野中","familyNameLang":"ja"}],"givenNames":[{"givenName":"喜久","givenNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"122","nameIdentifierScheme":"WEKO"}]}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"GABAおよびグルタミン酸作動性シナプス応答へのキセノンの作用","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"GABAおよびグルタミン酸作動性シナプス応答へのキセノンの作用"},{"subitem_title":"Effect of xenon on GABA and glutamatergic synaptic responses","subitem_title_language":"en"}]},"item_type_id":"10007","owner":"12","path":["71"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-03-08"},"publish_date":"2022-03-08","publish_status":"0","recid":"264","relation_version_is_last":true,"title":["GABAおよびグルタミン酸作動性シナプス応答へのキセノンの作用"],"weko_creator_id":"12","weko_shared_id":-1},"updated":"2024-04-18T02:03:48.243013+00:00"}